Colorado faces fellow Central division foe Nashville in a rematch of the opening round of the playoffs last season.
Watch live: Avs host West-leading Predators
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| Florida Panthers vs Boston Bruins | |
| Type: Puck Line – Status: OPEN | |
| Boston Bruins – 1P | -200 |
| Florida Panthers – 1P | +150 |
| Boston Bruins vs Florida Panthers | |
| Type: Series Winner – Status: OPEN | |
| Boston Bruins | +163 |
| Florida Panthers | -190 |
| Carolina Hurricanes vs New York Rangers | |
| Type: Series Total Games – Status: OPEN | |
| Under | -215 |
| Over | +175 |
| New York Rangers vs Carolina Hurricanes | |
| Type: Puck Line – Status: OPEN | |
| Carolina Hurricanes | +215 |
| New York Rangers | -260 |
| Colorado Avalanche vs Dallas Stars | |
| Type: Series Winner – Status: OPEN | |
| Colorado Avalanche | +102 |
| Dallas Stars | -122 |
| Dallas Stars vs Colorado Avalanche | |
| Type: Total – Status: OPEN | |
| Over | -122 |
| Under | +102 |
| Vancouver Canucks vs Edmonton Oilers | |
| Type: Total – Status: OPEN | |
| Over – 1P | -130 |
| Under – 1P | +100 |
| Vancouver Canucks vs Edmonton Oilers | |
| Type: Series Winner – Status: OPEN | |
| Edmonton Oilers | -270 |
| Vancouver Canucks | +220 |