Poking upset holes in the NFL’s Week 10 schedule is no easy task. Oddsmakers are emboldened by this point in any season after so many data points and revelations have occurred. As would-be bettors can see below, a combination of this confidence and some lopsided-looking matchups have created multiple
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| NFC Conference vs AFC Conference | |
| Type: Moneyline – Status: OPEN | |
| AFC Conference | -130 |
| NFC Conference | +100 |
| Philadelphia Eagles vs Green Bay Packers | |
| Type: Moneyline – Status: OPEN | |
| Philadelphia Eagles | -120 |
| Green Bay Packers | +100 |
| NFC Conference vs AFC Conference | |
| Type: Moneyline – Status: OPEN | |