After five weeks, fantasy owners of Dalvin Cook and Devonta Freeman are lamenting those draft picks, while those who gambled on Austin Ekeler and Tyler Boyd feel as if their fantasy IQs went up sharply. Week 6 constitutes a make-or-break moment for a host of players who have yet to live up to their preseason
FANTASY PLAYS: Starts and sits for a make or break week
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| NFC Conference vs AFC Conference | |
| Type: Moneyline – Status: OPEN | |
| AFC Conference | -130 |
| NFC Conference | +100 |
| Philadelphia Eagles vs Green Bay Packers | |
| Type: Moneyline – Status: OPEN | |
| Philadelphia Eagles | -120 |
| Green Bay Packers | +100 |
| NFC Conference vs AFC Conference | |
| Type: Moneyline – Status: OPEN | |
| AFC Conference | -130 |
| NFC Conference | +100 |