San Francisco coach Kyle Shanahan believed the improvements the team made leading into his third season would make the 49ers a contender. The early results have been extremely positive, with San Francisco opening the season with back-to-back road wins for the first time since 1989, capped by a dominant
49ers return home after successful road trip to start season
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| Philadelphia Eagles vs Green Bay Packers | |
| Type: Moneyline – Status: OPEN | |
| Philadelphia Eagles | -120 |
| Green Bay Packers | +100 |
| NFC Conference vs AFC Conference | |
| Type: Moneyline – Status: OPEN | |
| AFC Conference | -130 |
| NFC Conference | +100 |