The defending champs have the best chance at winning this year’s World Series, but a half-dozen rivals have cases for why they can prevent a repeat.
Who has the best shot at taking down the Astros?
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| Philadelphia Phillies vs San Francisco Giants | |
| Type: Runline – Status: OPEN | |
| Philadelphia Phillies | +100 |
| San Francisco Giants | -120 |
| Cleveland Guardians vs Detroit Tigers | |
| Type: Total – Status: OPEN | |
| Over – 1H | -135 |
| Under – 1H | +105 |
| Pittsburgh Pirates vs Los Angeles Angels | |
| Type: Moneyline – Status: OPEN | |
| Los Angeles Angels – 1H | +125 |
| Pittsburgh Pirates – 1H | -165 |
| Tampa Bay Rays vs Chicago White Sox | |
| Type: Runline – Status: OPEN | |
| Chicago White Sox | -150 |
| Tampa Bay Rays | +130 |
| Minnesota Twins vs Seattle Mariners | |
| Type: Total – Status: OPEN | |
| Over – 1H | -110 |
| Under – 1H | -120 |
| Chicago Cubs vs San Diego Padres | |
| Type: Moneyline – Status: OPEN | |
| Chicago Cubs | -114 |
| San Diego Padres | -106 |
| Kansas City Royals vs Milwaukee Brewers | |
| Type: Runline – Status: OPEN | |
| Milwaukee Brewers | -180 |
| Kansas City Royals | +155 |
| St. Louis Cardinals vs New York Mets | |
| Type: Moneyline – Status: OPEN | |
| New York Mets – 1H | -110 |
| St. Louis Cardinals – 1H | -120 |
| Oakland Athletics vs Texas Rangers | |
| Type: Total – Status: OPEN | |
| Under – 1H | -105 |
| Over – 1H | -125 |
| Los Angeles Dodgers vs Miami Marlins | |
| Type: Total – Status: OPEN | |
| Under – 1I | -275 |
| Over – 1I | +190 |
| Chunichi Dragons vs Yomiuri Giants | |
| Type: Total – Status: OPEN | |
| Over | -120 |
| Under | -110 |
| Hanshin Tigers vs Hiroshima Toyo Carp | |
| Type: Runline – Status: OPEN | |
| Hiroshima Toyo Carp | -220 |
| Hanshin Tigers | +165 |
| Chiba Lotte Marines vs Saitama Seibu Lions | |
| Type: Total – Status: OPEN | |
| Over | -115 |
| Under | -115 |
| Fukuoka SoftBank Hawks vs Hokkaido Nippon-Ham Fighters | |
| Type: Runline – Status: OPEN | |
| Hokkaido Nippon-Ham Fighters | -185 |
| Fukuoka SoftBank Hawks | +140 |
| Kiwoom Heroes vs Doosan Bears | |
| Type: Runline – Status: OPEN | |
| Kiwoom Heroes | -115 |
| Doosan Bears | -115 |
| KT Wiz vs NC Dinos | |
| Type: Total – Status: OPEN | |
| Over | -125 |
| Under | -105 |
| Samsung Lions vs Kia Tigers | |
| Type: Moneyline – Status: OPEN | |
| Kia Tigers | -175 |
| Samsung Lions | +130 |
| Lotte Giants vs Hanwha Eagles | |
| Type: Total – Status: OPEN | |
| Over | -115 |
| Under | -115 |
| LG Twins vs SSG Landers | |
| Type: Runline – Status: OPEN | |
| LG Twins | -120 |
| SSG Landers | -110 |