David Ortiz will play first base for Boston when the World Series resumes Saturday night, and Kevin Youkilis will be benched as the Red Sox adjust to life without a designated hitter. Mike Lowell will remain at third for the Red Sox, who have a 2-0 Series lead against the Colorado Rockies. Ortiz, bothered by a left knee that will need surgery, worked out at first base Friday.
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| Tigres de Quintana Roo vs El Aguila de Veracruz | |
| Type: Runline – Status: OPEN | |
| Tigres de Quintana Roo | -180 |
| El Aguila de Veracruz | +125 |
| Boston Red Sox vs Chicago Cubs | |
| Type: Total – Status: OPEN | |
| Over – 1I | +250 |
| Under – 1I | -360 |
| Rieleros de Aguascalientes vs Sultanes de Monterrey | |
| Type: Total – Status: OPEN | |
| Over | -115 |
| Under | -125 |
| Acereros de Monclova vs Generales De Durango | |
| Type: Runline – Status: OPEN | |
| Acereros de Monclova | +110 |
| Generales De Durango | -155 |
| Piratas de Campeche vs Guerreros de Oaxaca | |
| Type: Moneyline – Status: OPEN | |
| Piratas de Campeche | -115 |
| Guerreros de Oaxaca | -125 |
| Olmecas de Tabasco vs Diablos Rojos del México | |
| Type: Moneyline – Status: OPEN | |
| Diablos Rojos del México | -170 |
| Olmecas de Tabasco | +120 |
| Toros de Tijuana vs Saraperos de Saltillo | |
| Type: Total – Status: OPEN | |
| Under | -110 |
| Over | -130 |
| Tecolotes de los Dos Laredos vs Algodoneros del Unión Laguna | |
| Type: Moneyline – Status: OPEN | |
| Algodoneros del Unión Laguna | +140 |
| Tecolotes de los Dos Laredos | -200 |
| Baltimore Orioles vs New York Yankees | |
| Type: Runline – Status: OPEN | |
| New York Yankees – 1H | -125 |
| Baltimore Orioles – 1H | -105 |
| Miami Marlins vs Washington Nationals | |
| Type: Moneyline – Status: OPEN | |
| Washington Nationals – 1I | +115 |
| Miami Marlins – 1I | -150 |
| Detroit Tigers vs St. Louis Cardinals | |
| Type: Moneyline – Status: OPEN | |
| St. Louis Cardinals | -112 |
| Detroit Tigers | -108 |
| Toronto Blue Jays vs Kansas City Royals | |
| Type: Runline – Status: OPEN | |
| Kansas City Royals – 1H | -120 |
| Toronto Blue Jays – 1H | -110 |
| Milwaukee Brewers vs Tampa Bay Rays | |
| Type: Total – Status: OPEN | |
| Over – 1H | -125 |
| Under – 1H | -105 |
| Chicago White Sox vs Minnesota Twins | |
| Type: Moneyline – Status: OPEN | |
| Minnesota Twins – 1H | -165 |
| Chicago White Sox – 1H | +125 |
| Los Angeles Angels vs Philadelphia Phillies | |
| Type: Total – Status: OPEN | |
| Over | +100 |
| Under | -120 |
| Arizona Diamondbacks vs Los Angeles Dodgers | |
| Type: Moneyline – Status: OPEN | |
| Los Angeles Dodgers – 1H | -145 |
| Arizona Diamondbacks – 1H | +110 |
| San Diego Padres vs Cincinnati Reds | |
| Type: Total – Status: OPEN | |
| Over | -120 |
| Under | +100 |
| Seattle Mariners vs Atlanta Braves | |
| Type: Moneyline – Status: OPEN | |
| Atlanta Braves | -154 |
| Seattle Mariners | +129 |
| Oakland Athletics vs Pittsburgh Pirates | |
| Type: Moneyline – Status: OPEN | |
| Pittsburgh Pirates – 1H | -135 |
| Oakland Athletics – 1H | +105 |