Oklahoma won another Big 12 title and made it to the College Football Playoff again in its first season without coach Bob Stoops on the sideline. The Sooners, who have won the past three Big 12 titles with quarterback Baker Mayfield, will now be trying to do it again without the Heisman Trophy winner
Oklahoma favored again going into Big 12 football media days
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| NFC Conference vs AFC Conference | |
| Type: Moneyline – Status: OPEN | |
| AFC Conference | -130 |
| NFC Conference | +100 |
| Philadelphia Eagles vs Green Bay Packers | |
| Type: Moneyline – Status: OPEN | |
| Philadelphia Eagles | -120 |
| Green Bay Packers | +100 |
| NFC Conference vs AFC Conference | |
| Type: Moneyline – Status: OPEN | |
| AFC Conference | -130 |
| NFC Conference | +100 |