The Cincinnati Bengals placed running back Joe Mixon on injured reserve Saturday.
| Philadelphia Eagles vs Seattle Seahawks | |
| Type: Point Spread - Status: OPEN | |
| Seattle Seahawks - 2Q | -120 |
| Philadelphia Eagles - 2Q | -110 |
| Pittsburgh Steelers vs Baltimore Ravens | |
| Type: Total - Status: OPEN | |
| Over - 1H | +100 |
| Under - 1H | -120 |
| Miami Dolphins vs Cincinnati Bengals | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |
| Tennessee Titans vs Cleveland Browns | |
| Type: Total - Status: OPEN | |
| Over | -110 |
| Under | -110 |
| Atlanta Falcons vs New Orleans Saints | |
| Type: Moneyline - Status: OPEN | |
| Atlanta Falcons | +160 |
| New Orleans Saints | -180 |
| Minnesota Vikings vs Jacksonville Jaguars | |
| Type: Moneyline - Status: OPEN | |
| Minnesota Vikings | -500 |
| Jacksonville Jaguars | +350 |
| Houston Texans vs Indianapolis Colts | |
| Type: Total - Status: OPEN | |
| Over | -105 |
| Under | -115 |
| New York Jets vs Las Vegas Raiders | |
| Type: Total - Status: OPEN | |
| Over | -110 |
| Under | -110 |
| Arizona Cardinals vs Los Angeles Rams | |
| Type: Point Spread - Status: OPEN | |
| Arizona Cardinals | -130 |
| Los Angeles Rams | +110 |
| Los Angeles Chargers vs New England Patriots | |
| Type: Point Spread - Status: OPEN | |
| Los Angeles Chargers | -115 |
| New England Patriots | -105 |
| Kansas City Chiefs vs Denver Broncos | |
| Type: Point Spread - Status: OPEN | |
| Kansas City Chiefs - 1Q | -115 |
| Denver Broncos - 1Q | -115 |
| San Francisco 49ers vs Buffalo Bills | |
| Type: Point Spread - Status: OPEN | |